Paliperidone Palmitate for Schizophrenia

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Pharmacoeconomic analysis of paliperidone palmitate for treating schizophrenia in Greece

BACKGROUND Patients having chronic schizophrenia with frequent relapses and hospitalizations represent a great challenge, both clinically and financially. Risperidone long-acting injection (RIS-LAI) has been the main LAI atypical antipsychotic treatment in Greece. Paliperidone palmitate (PP-LAI) has recently been approved. It is dosed monthly, as opposed to biweekly for RIS-LAI, but such advant...

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Paliperidone palmitate versus oral antipsychotics in recently diagnosed schizophrenia

OBJECTIVE Relapse and acute exacerbation are common in schizophrenia and may impact treatment response and outcome. Evidence is conflicting in respect to superiority of long-acting injectable antipsychotic therapies versus oral antipsychotics in relapse prevention. This randomized controlled study assessed the efficacy of paliperidone palmitate versus oral antipsychotics for relapse prevention....

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PM394. The outcome of paliperidone palmitate in schizophrenia

Objective: This study is to evaluate the efficacy, functional improvements, and insight improvements in schizophrenic patients with long-acting injectable paliperidone palmitate (PP) treatment. Method: This is a 12-month, open-label, study from Taiwan, included 13 schizophrenic patients, between 17 and 72 years of age. Treatment response was assessed by Positive and Negative Syndrome Scale (PAN...

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Manic Symptoms during a Switch from Paliperidone ER to Paliperidone Palmitate in a Patient with Schizophrenia

Some antipsychotic drugs have treatment efficacy for mania and bipolar disorder. However, these drugs may rarely cause manic symptoms in some schizophrenic patients. We hereby report a 22-year-old female patient with schizophrenia who experienced a manic episode during a switch from paliperidone ER to paliperidone palmitate. This case is an important reminder that an abrupt switch from oral pal...

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Cost-Effectiveness of Paliperidone Palmitate Versus other Antipsychotics for the Treatment of Schizophrenia in France.

METHODS • Schizophrenia is a severe mental disorder, characterized by profound disruptions in thinking and affecting language, perception, and the sense of self.[1] This disabling and emotionally devastating illness is manifested by ‘positive’ (e.g. delusion, hallucinations) and ‘negative’ (e.g. blunted affect, alogia) symptoms. • In 2005, the prevalence of schizophrenia patients in France was ...

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ژورنال

عنوان ژورنال: Schizophrenia Bulletin

سال: 2012

ISSN: 0586-7614,1745-1701

DOI: 10.1093/schbul/sbs099